Spleen Size in Idiopathic and Heritable Pulmonary Arterial Hypertension
نویسندگان
چکیده
منابع مشابه
Spleen size in idiopathic and heritable pulmonary arterial hypertension.
BACKGROUND It is unknown whether the spleen size correlates with disease severity and outcome in patients with idiopathic and heritable pulmonary arterial hypertension (PAH). OBJECTIVES To determine the prevalence of splenomegaly in PAH and assess whether it correlates with severity of disease and outcome. METHODS We identified subjects with either heritable or idiopathic PAH who had Dopple...
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BACKGROUND Anaemia is common in left heart failure and is associated with a poorer outcome. Many patients with pulmonary arterial hypertension (PAH) are anaemic or iron-deficient. This study was performed to investigate the prevalence of iron deficiency in PAH and to identify possible causes. METHODS All patients with idiopathic or heritable PAH diagnosed in 1995-2008 were identified. Control...
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BACKGROUND The prevalence and prognostic implications of hypoxemia either at rest or during six-minute walk test (6MWT) in patients with idiopathic or heritable pulmonary arterial hypertension (IPAH or HPAH) have not been systemically studied. OBJECTIVES We sought to determine the prevalence, phenotypic and prognostic implications of hypoxemia in patients with IPAH and HPAH. METHODS Patient...
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cytometry analysis of BAL cells. Table 1 integrates information given in our published paper, clearly demonstrating that the number of BAL neutrophils was fair in our case series. This unfortunately prevented a definitive evaluation of whether polymorph nucleates represent a source of IL-17. Nonetheless, as shown in figure 1, in selected cases with a significant number of BAL neutrophils (two s...
متن کاملImpaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension.
BACKGROUND Beyond their role as innate immune effectors, natural killer (NK) cells are emerging as important regulators of angiogenesis and vascular remodeling. Pulmonary arterial hypertension (PAH) is characterized by severe pulmonary vascular remodeling and has long been associated with immune dysfunction. Despite this association, a role for NK cells in disease pathology has not yet been des...
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ژورنال
عنوان ژورنال: Respiration
سال: 2013
ISSN: 1423-0356,0025-7931
DOI: 10.1159/000339423